Defense Health Program – Department of Defense Peer Reviewed Medical Research Program Funding Opportunities for Fiscal Year 2020 (FY20)

The FY20 Defense Appropriations Act provides funding to the Department of Defense Peer Reviewed Medical Research Program (PRMRP) to support to support medical research projects of clear scientific merit and direct relevance to military health. As directed by the Office of the Assistant Secretary of Defense for Health Affairs, the Defense Health Agency J9, Research and Development Directorate manages the Defense Health Program (DHP) Research, Development, Test, and Evaluation (RDT&E) appropriation. The managing agent for the anticipated Program Announcements/Funding Opportunities is the Congressionally Directed Medical Research Programs (CDMRP) at the U.S. Army Medical Research and Development Command (USAMRDC).

The FY20 PRMRP Program Announcements and General Application Instructions for the following award mechanisms are posted on the Grants.gov website.   

The vision and mission of the PRMRP is improve the health, care, and well-being of all military Service members, Veterans, and beneficiaries by encouraging, identifying, selecting, and managing medical research projects of clear scientific merit and direct relevance to military health.

Congressionally Directed Topic Areas: All applications submitted to the PRMRP must address at least one of the FY20 PRMRP Congressionally directed topic areas. The FY20 PRMRP Topic Areas are as follows:

Arthritis Burn Pit Exposure
Chronic Migraine Post-Traumatic Headache
Congestive Heart Disease Diabetes
Dystonia Eating Disorder
Emerging Viral Disease Endometriosis
Epidermolysia Bullosa Familial Hypercholesterolemia
Fibrous Dysplasia Focal Segmental Glomerulosclerosis
Food Allergies Fragile X
Frontotemporal Degeneration Hepatitis B
Guillain-Barre Syndromemorrhage Control Immunomonitoring of Intestinal Transplants
Hydrocephalus Inflammatory Bowel Diseases
Interstitial Cystitis Metals Toxicology
Mitchondrial Disease Musculoskeletal Health
Myalgic Encephalomyelitis Chronic Fatigue Syndrome
Myotonic Dystrophy Nutrition Optimization
Pancreatitis Pathogen-Inactivated Blood Products
Plant Based Vaccines Polycystic Kidney Disease
Pressure Ulcers Pulmonary Fibrosis
Resilience Training Respiratory Health
Rheumatoid Arthritis Sleep Disorders and Restriction
Spinal Muscular Atrophy Sustained Release Drug Delivery
Vascular Malformations Women’s Heart Disease

Discovery Award – Letter of Intent due April 16, 2020

Postdoctoral fellow or clinical fellow (or equivalent) and above:

  • Supports the exploration of a highly innovative new concept or untested theory.
  • Not intended to support the logical progression of an already established line of questioning.
  • Clinical trials will not be funded.
  • Reviewers will be blinded to the identity of the Principal Investigator (PI), collaborators, and their organization(s).
  • Maximum of $200,000 for direct costs (plus indirect costs)
  • Maximum period of performance of 2 years.

Focused Program Award – Pre-proposal due April 23, 2020

Full Professor level or above (or equivalent):

  • Pre-proposal submission is required; application submission is by invitation only.
  • Supports a synergistic, multidisciplinary research program of at least four distinct but complementary projects addressing an overarching goal.
  • Projects should work together to answer critical questions, resolve differing hypotheses, and translate laboratory findings to clinical applications.
  • Projects may range from exploratory/hypothesis-developing through small-scale clinical trials that together will address the overarching goal/question.
  • Research team of highly qualified, multidisciplinary project leaders should be led by a PI with demonstrated success in directing large, focused projects.
  • Maximum of $7.2 million for direct costs (plus indirect costs).
  • Maximum period of performance of 4 years.

Investigator-Initiated Research Award – Pre-proposal due April 23, 2020

Assistant Professor level or above (or equivalent):
  • Pre-proposal submission is required; application submission is by invitation only.
  • Supports research that will make an original and important contribution to the field of research or patient care in the topic area(s) of interest.
  • Partnering PI Option available.
  • Clinical trials will not be funded.
  • Maximum of $1.6 million for direct costs (plus indirect costs).
  • Maximum of $2 million for direct costs (plus indirect costs) for applications including a Partnering PI Option.
  • Maximum period of performance is 4 years.

Technology/Therapeutic Development Award – Pre-proposal due April 23, 2020

Assistant Professor level or above (or equivalent):

  • Pre-proposal submission is required; application submission is by invitation only.
  • Supports the translation of promising pre-clinical findings into clinical applications for prevention, detection, diagnosis, treatment, or quality of life.
  • Product-oriented (e.g., device, drug, clinical guidelines). The product(s) to be developed may be a tangible item such as a pharmacologic agent (drugs or biologics) or device, or a knowledge-based product.
  • Clinical trials will not be funded.
  • Maximum of $4 million for direct costs (plus indirect costs).
  • Maximum period of performance is 4 years.

A pre-application is required and must be submitted through the electronic Biomedical Research Application Portal (eBRAP) at https://eBRAP.org prior to the pre-application deadline. All applications must conform to the final Program Announcements and General Application Instructions available for electronic downloading from the Grants.gov website.  The application package containing the required forms for each award mechanism will also be found on Grants.gov. A listing of all CDMRP and other USAMRDC extramural funding opportunities can be obtained on the Grants.gov website by performing a basic search using CFDA Number 12.420. 

For email notification when Program Announcements are released, subscribe to program-specific news and updates under “Email Subscriptions” on the eBRAP homepage at https://eBRAP.org.  For more information about the PRMRP or other CDMRP-administered programs, please visit the CDMRP website.

Point of Contact: CDMRP Help Desk
301-682-5507
help@eBrap.org

Multidisciplinary Research Program of the University Research Initiative

This FY 2021 Air Force Multidisciplinary Research Program of the University Research Initiative (MURI) competition is open only to, and proposals are to be submitted only by, US institutions of higher education (universities) with degree-granting programs in science and/or engineering, including DoD institutions of higher education. To the extent that it is a part of a US institution of higher education and is not designated as a Federally Funded Research and Development Center (FFRDC), a University Affiliated Research Center (UARC) or other University Affiliated Laboratory (UAL) is eligible to submit a proposal to this MURI competition and/or receive MURI funds. Ineligible organizations (e.g., industry, DoD laboratories, FFRDCs, and foreign entities) may collaborate on the research but may not receive MURI funds directly or via sub award. When additional funding for an ineligible organization is necessary to make the proposed collaboration possible, such funds may be identified via a separate proposal from that organization. This supplemental proposal shall be attached to the primary MURI proposal and will be evaluated in accordance with the MURI review criteria by the responsible Research Topic Chief. If approved, the supplemental proposal may be funded using non-MURI or non-Government funds.

DOD’s MURI program addresses high-risk basic research and attempts to understand or achieve something that has never been done before. The program was initiated over 25 years ago and it has regularly produced significant scientific breakthroughs with far reaching consequences to the fields of science, economic growth, and revolutionary new military technologies. Key to the program’s success is the close management of the MURI projects by Service program officers and their active role in providing research guidance.

Detailed descriptions of the topics and the Topic Chief for each can be found in Section II. I, entitled, “SPECIFIC MURI TOPICS,” (page 39 of 79 in the FOA document). The detailed descriptions are intended to provide the applicant a frame of reference and are not meant to be restrictive to the possible approaches to achieving the goals of the topic and the program. Innovative ideas addressing these research topics are highly encouraged.

BROAD AGENCY ANNOUNCEMENT (BAA) for Extramural Biomedical Research and Development

This BAA is intended to solicit extramural research and development ideas using the authority provided by United States Code, Title 10, Section 2358. This BAA is issued under the provisions of the Competition in Contracting Act of 1984 (Public Law 98-369), as implemented in Federal Acquisition Regulation 6.102(d) (2) and 35.016 and in DoD Grant and Agreement Regulations (DoDGARs) 22.315. In accordance with FAR 6.102, projects funded under this BAA must be for basic and applied research to support scientific study and experimentation directed toward advancing the state-of-the-art or increasing knowledge or understanding rather than focusing on development of a specific system or hardware solution. Research and development funding through this BAA are intended and expected to benefit and inform both military and civilian medical practice and knowledge.

This BAA provides a general description of USSOCOM’s research and development programs, including research areas of interest, evaluation and selection criteria, pre-proposal/pre-application and full proposal/application preparation instructions, and general administrative information. Submission of a pre-proposal/pre-application is required. After review, if the USSOCOM is interested in receiving a full proposal/application, the Applicant or Offeror will be invited to submit a full proposal or full application. Specific submission information and additional administrative requirements can be found in the document titled “General Submission Instructions” available in Grants.gov along with this BAA.

USSOCOM utilizes the tools and processes provided by Congressionally Directed Medical Research Programs (CDMRP). The CDMRP manages the electronic Biomedical Research Application Portal (eBRAP) system and retrieval and processing of full proposal/application submissions from Grants.gov. Refer to Section II.G, Agency Contacts, for additional information.

FY2021 Defense University Instrumentation Program (DURIP)

This announcement seeks proposals from universities to purchase equipment and instrumentation in support of research in areas of interest to the Department of Defense.

DoD interests include the areas of research supported by the Army Research Office (ARO), the Office of Naval Research (ONR), and the Air Force Office of Scientific Research (AFOSR), hereafter generally referred to collectively as “we,” “our,” “us,” or “administering agency.” We use “administering agency” to provide a generic reference to any of the administering agencies.

A central purpose of the DURIP is to provide equipment and instrumentation to enhance research related education in areas of interest and priority to the DoD. Therefore, your proposal must address the impact of the equipment or instrumentation on your institution’s ability to educate students through research in disciplines important to DoD missions.

ADMINISTERING AGENCY – HOW TO FIND RESEARCH INTERESTS

Army Research Office (ARO)

Navigate to the “Broad Agency Announcements” section to see the most recent ARL or ARO Core Broad Agency Announcement for Basic and Applied Scientific Research.

Office of Naval Research (ONR)

Select “Work With Us” and then “Funding Opportunities” to see the Long Range Broad Agency Announcement for Navy and Marine Corps Science and Technology, BAA N00014-20-S-B001.

Air Force Office of Scientific Research (AFOSR)

Navigate to https://www.grants.gov/web/grants/view-opportunity.html?oppId=314753 to view the “Research Interests of the Air Force Office of Scientific Research,” BAA FA9550-19-S-0003.

You must refer to the websites cited above for detailed technical information and the technical goals. DoD encourages you to contact the Program Managers listed in the cited announcements before submitting proposals to explore research areas of mutual interest to you and us.

You may submit a single DURIP proposal to more than one administering agency; however, only one administering agency will fund it, if selected. There is no limit on the total number of different proposals you can submit. There is no limit to the number of awards a single applicant organization can receive under this competition. DoD discusses this again in sections C.3.b Amount of Requested DoD Funding and D.4.g Submission to Multiple Administering Agencies.

DoD reserves the right to select and fund for award, all, some, part, or none of the proposals received. There is no guarantee of award.

New Funding Opportunity: Department of Defense National Defense Education Program

The Department of Defense (DoD) recently published the RFP for the National Defense Education Program (NDEP) for Science, Technology, Engineering, and Mathematics (STEM) Education, Outreach, and Workforce Initiative Programs, Fiscal Year 2020.

DOD seeks innovative applications on mechanisms to implement STEM education, outreach, and/or workforce initiative programs, here onto will be referred as STEM activities. The Department intends to award multiple grants, subject to the availability of funds. Each individual award will be up to a maximum of $3,000,000, for a period of up to three years. Applications for larger amounts may be considered on a case-by-case basis.

The Federal STEM Strategy states, “The pace of innovation is accelerating globally, and with it the competition for scientific and technical talent. Now more than ever the innovation capacity of the United States—and its prosperity and security—depends on an effective and inclusive STEM education ecosystem”. In addition, the National Defense Strategy has called for the Department of Defense to make significant investments in science and technology modernization priority areas to meet key capability and capacity needs. 

DoD is the largest employer of scientists and engineers in the United States. Therefore, the Department must maintain a robust pipeline of STEM talent by investing in pre-kindergarten through undergraduate STEM activities to ensure the DoD has enduring access to the best and brightest talent. The NDEP enables the DoD to cultivate and access high-quality STEM personnel vital to national defense now and in the future. This solicitation seeks innovative approaches to support DoD STEM education, outreach, and workforce development that aligns with DoD and Federal STEM Strategic Plans.