The FY20 Defense Appropriations Act provides funding to the Department of Defense Peer Reviewed Medical Research Program (PRMRP) to support to support medical research projects of clear scientific merit and direct relevance to military health. As directed by the Office of the Assistant Secretary of Defense for Health Affairs, the Defense Health Agency J9, Research and Development Directorate manages the Defense Health Program (DHP) Research, Development, Test, and Evaluation (RDT&E) appropriation. The managing agent for the anticipated Program Announcements/Funding Opportunities is the Congressionally Directed Medical Research Programs (CDMRP) at the U.S. Army Medical Research and Development Command (USAMRDC).

The FY20 PRMRP Program Announcements and General Application Instructions for the following award mechanisms are posted on the Grants.gov website.   

The vision and mission of the PRMRP is improve the health, care, and well-being of all military Service members, Veterans, and beneficiaries by encouraging, identifying, selecting, and managing medical research projects of clear scientific merit and direct relevance to military health.

Congressionally Directed Topic Areas: All applications submitted to the PRMRP must address at least one of the FY20 PRMRP Congressionally directed topic areas. The FY20 PRMRP Topic Areas are as follows:

Arthritis	Burn Pit Exposure
Chronic Migraine	Post-Traumatic Headache
Congestive Heart Disease	Diabetes
Dystonia	Eating Disorder
Emerging Viral Disease	Endometriosis
Epidermolysia Bullosa	Familial Hypercholesterolemia
Fibrous Dysplasia	Focal Segmental Glomerulosclerosis
Food Allergies	Fragile X
Frontotemporal Degeneration	Hepatitis B
Guillain-Barre Syndromemorrhage Control	Immunomonitoring of Intestinal Transplants
Hydrocephalus	Inflammatory Bowel Diseases
Interstitial Cystitis	Metals Toxicology
Mitchondrial Disease	Musculoskeletal Health
Myalgic Encephalomyelitis	Chronic Fatigue Syndrome
Myotonic Dystrophy	Nutrition Optimization
Pancreatitis	Pathogen-Inactivated Blood Products
Plant Based Vaccines	Polycystic Kidney Disease
Pressure Ulcers	Pulmonary Fibrosis
Resilience Training	Respiratory Health
Rheumatoid Arthritis	Sleep Disorders and Restriction
Spinal Muscular Atrophy	Sustained Release Drug Delivery
Vascular Malformations	Women’s Heart Disease

Discovery Award – Letter of Intent due April 16, 2020

Postdoctoral fellow or clinical fellow (or equivalent) and above:

• Supports the exploration of a highly innovative new concept or untested theory.
• Not intended to support the logical progression of an already established line of questioning.
• Clinical trials will not be funded.
• Reviewers will be blinded to the identity of the Principal Investigator (PI), collaborators, and their organization(s).
• Maximum of $200,000 for direct costs (plus indirect costs)
• Maximum period of performance of 2 years.

Focused Program Award – Pre-proposal due April 23, 2020

Full Professor level or above (or equivalent):

• Pre-proposal submission is required; application submission is by invitation only.
• Supports a synergistic, multidisciplinary research program of at least four distinct but complementary projects addressing an overarching goal.
• Projects should work together to answer critical questions, resolve differing hypotheses, and translate laboratory findings to clinical applications.
• Projects may range from exploratory/hypothesis-developing through small-scale clinical trials that together will address the overarching goal/question.
• Research team of highly qualified, multidisciplinary project leaders should be led by a PI with demonstrated success in directing large, focused projects.
• Maximum of $7.2 million for direct costs (plus indirect costs).
• Maximum period of performance of 4 years.

Investigator-Initiated Research Award – Pre-proposal due April 23, 2020

Assistant Professor level or above (or equivalent):

• Pre-proposal submission is required; application submission is by invitation only.
• Supports research that will make an original and important contribution to the field of research or patient care in the topic area(s) of interest.
• Partnering PI Option available.
• Clinical trials will not be funded.
• Maximum of $1.6 million for direct costs (plus indirect costs).
• Maximum of $2 million for direct costs (plus indirect costs) for applications including a Partnering PI Option.
• Maximum period of performance is 4 years.

Technology/Therapeutic Development Award – Pre-proposal due April 23, 2020

Assistant Professor level or above (or equivalent):

• Pre-proposal submission is required; application submission is by invitation only.
• Supports the translation of promising pre-clinical findings into clinical applications for prevention, detection, diagnosis, treatment, or quality of life.
• Product-oriented (e.g., device, drug, clinical guidelines). The product(s) to be developed may be a tangible item such as a pharmacologic agent (drugs or biologics) or device, or a knowledge-based product.
• Clinical trials will not be funded.
• Maximum of $4 million for direct costs (plus indirect costs).
• Maximum period of performance is 4 years.

A pre-application is required and must be submitted through the electronic Biomedical Research Application Portal (eBRAP) at https://eBRAP.org prior to the pre-application deadline. All applications must conform to the final Program Announcements and General Application Instructions available for electronic downloading from the Grants.gov website.  The application package containing the required forms for each award mechanism will also be found on Grants.gov. A listing of all CDMRP and other USAMRDC extramural funding opportunities can be obtained on the Grants.gov website by performing a basic search using CFDA Number 12.420. 

For email notification when Program Announcements are released, subscribe to program-specific news and updates under “Email Subscriptions” on the eBRAP homepage at https://eBRAP.org.  For more information about the PRMRP or other CDMRP-administered programs, please visit the CDMRP website.

Point of Contact: CDMRP Help Desk
301-682-5507
help@eBrap.org