The Patient-Centered Outcomes Research Institute (PCORI) seeks to fund multiple high quality clinical studies that compare the effectiveness of evidence-based treatments for relief of common symptoms experienced by patients with serious, advanced illness. Prior research on symptom management has shown the potential for clinically significant improvements in quality of life, symptom burden, utilization of hospital services, and caregiver stress. Additional evidence from head-to-head studies is needed to improve the evidence base about how various symptom management approaches convey benefits and harms upon patients.

Further details will be available in the full announcement which will be released on June 23, 2017. Please email sciencequestions@pcori.org with any questions related to this funding announcement.