The CRRP seeks to enhance medical capabilities at the point of greatest need in order to save the most lives in future combat scenarios, which may be complicated by limited resources, austere conditions, and/or mass casualty events. The intent of the FY19 CRRP RDTRA is to support research that will accelerate the movement of promising ideas into clinical applications, including healthcare products, technologies, and/or practice guidelines. Applicants may leverage existing resources in translational research to address high-impact research ideas or unmet needs in delivering lifesaving care to the Warfighter during prolonged and en route care in austere and combat environments. Research of interest may include knowledge products, “knowledge resulting from research with the potential to improve individual or public health,”2 and solutions that can accelerate the introduction of military-relevant health products or technologies into clinical and/or operational use. For this award mechanism, the definition of “leveraging” is as follows: An investigator basing a research project on existing resources in order to amplify potential gains in knowledge or accelerate technical maturity. Projects should consider the varied expertise levels of the medical providers and the possible diverse environmental conditions in combat situations. Proposal/application submissions are encouraged to include characteristics relevant to military use in non-hospital settings in theater, but submissions that propose solutions to advance civilian trauma care are not precluded, since civilian trauma care frequently informs and influences trauma care in the military, and vice versa.

Submission Dates and Times:

• Pre-Application (Letter of Intent) Submission Deadline: 5:00 p.m. Eastern time (ET), October 23, 2019
• Proposal/Application Submission Deadline: 11:59 p.m. ET, November 13, 2019

To meet the intent of the award mechanism, proposals submitted to the FY19 CRRP RDTRA must address at least one of the Focus Areas below:

• Scalable solutions for wound care that can address prevention of bleeding and infection, delivery of therapeutics, and promotion of healing
• Decision-support solutions, such as algorithms, artificial intelligence, deep learning, telemedicine, etc. for triage and management of severely injured Warfighters, to include management and monitoring of:
  • Acute pain, to include non-opioid solutions
  • Hemorrhage and resuscitation (e.g., airway management, control of bleeding, sedation, etc.)
  • Multi-casualty events when delayed evacuation exceeds available capability and/or capacity, in order to extend or enhance provider capabilities
• Solutions that address hemorrhage control, including:
  • Non-compressible torso hemorrhage
  • Alternatives to optimize logistics and administration of blood products to the Warfighter
• Wearable sensors with multiple capabilities to identify and monitor medical management of injuries and/or exposures, such as:
  • Environmental exposures
  • Onset of infection, including sepsis
  • Physiological status and stress monitoring tools (heart rate, blood pressure, respiration)
  • Neurological injury
  • Point-of-care imaging in prolonged field care

The anticipated direct costs budgeted for the entire period of performance for an FY19 CRRP RDTRA will not exceed $1,500,000.

Additional information about this funding opportunity, including the BAA, can be found on grants.gov.