Link to the page to search for grants: https://www.grants.gov/web/grants/search-grants.html

National Institutes of Health (NIH)Components of Participating Organizations

National Institute of Neurological Disorders and Stroke (NINDS)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute on Drug Abuse (NIDA)
National Institute of Environmental Health Sciences (NIEHS)

Funding Opportunity Title

Summer Research Education Experience Program (R25 Clinical Trial Not Allowed)

Activity Code

R25 Education Projects

Announcement Type

Reissue of PAR-15-184

Related Notices

None

Funding Opportunity Announcement (FOA) Number

PAR-19-197

Companion Funding Opportunity

None

Number of Applications

See Section III. 3. Additional Information on Eligibility.

Catalog of Federal Domestic Assistance (CFDA) Number(s)

93.113, 93.286, 93.273, 93.279, 93.853 

Funding Opportunity Purpose

 The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH.  The over-arching goal of this R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nation’s biomedical, behavioral and clinical research needs. 

Key Dates

Posted Date

February 25, 2019

Open Date (Earliest Submission Date)

March 23, 2019

Letter of Intent Due Date(s)

30 days prior to application due date

Application Due Date(s)

April 23, 2019, March 17, 2020, March 17 2021, by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on these dates. 

Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

AIDS Application Due Date(s)

May 7, 2019, May 7, 2020, May 7, 2021, by 5:00 PM local time of applicant organization. All types of AIDS and AIDS-related applications allowed for this funding opportunity announcement are due on these dates.

Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

Scientific Merit Review

July 2019, July 2020, July 2021

Advisory Council Review

October 2019, October 2020, October 2021

Earliest Start Date

December 2019, December 2020, December 2021

Expiration Date

May 8, 2021

Due Dates for E.O. 12372

Not Applicable

Required Application Instructions

It is critical that applicants follow the Research (R) Instructions in the SF424 (R&R) Application Guide except where instructed to do otherwise (in this FOA or in a Notice from the NIH Guide for Grants and Contracts). Conformance to all requirements (both in the Application Guide and the FOA) is required and strictly enforced. Applicants must read and follow all application instructions in the Application Guide as well as any program-specific instructions noted in Section IV. When the program-specific instructions deviate from those in the Application Guide, follow the program-specific instructions.

Applications that do not comply with these instructions will not be reviewed

Please visit: https://grants.nih.gov/grants/guide/pa-files/PAR-19-197.html for more details.

Due Date: April 10, 2019

NineSights Community – Request for Proposal: ‪Transforming the Future of Tobacco Cessation & Reduction‬

Opportunity

GSK will award research grants, joint development opportunities, and licensing agreements with selected partners with compelling approaches that fit with GSK’s vision.

Selected partners will gain access to the GSK Smokers’ Health Leadership team for further discussions under a confidentiality agreement with the ultimate goal of funding specific projects or research initiatives.

Financials

Partner approaches will support GSK’s Nicotine Replacement Therapy (NRT) platforms.SOLUTION PROVIDER HELP DESK USA:Email: phd@ninesigma.com

RFP Title
Transforming the Future of Tobacco Cessation & Reduction

RFP Description

NineSigma, representing GSK Consumer Healthcare, invites proposals for new technologies to ENHANCE or REIMAGINE current approaches to tobacco cessation and reduction.

Background

GSK Consumer Healthcare currently is the largest global marketer of nicotine replacement therapies (NRT) for smoking cessation. We serve patients in over 20 countries, including the US, Canada, across Europe, and Australia.

GSK Consumer Healthcare strives to transform the future of self-care. We hope to leverage the wisdom of experts within the fields of nicotine and tobacco research to identify areas of critical and emerging unmet needs within the tobacco cessation and reduction space and collaborate with key scientific partners to help deliver upon them.

Key Success Criteria

The challenge focuses around the following areas of interest for GSK. Those with technologies that can fit or be adapted to any of these areas are asked to submit a brief proposal through the NineSights web portal (details below).

Differentiated Nicotine Replacement Therapy

GSK seeks differentiated oral and transdermal dosage forms for our NRT products as part of our Smokers’ Health franchise.  Innovation may deliver superior efficacy or enhanced user experience.

Additionally, we are always seeking to improve how patients utilize our products by innovating in areas such as (but not limited to):

• Cessation and reduction of Electronic Nicotine Delivery Systems (ENDS)
• Novel dosage forms
• Improving compliance and adherence
• Research related to the efficacy or effectiveness of NRT
• Increasing access and availability to NRT

Digital Health & Behavioral Support Platforms

Behavioral support is shown to improve a smoker’s chances of quitting. GSK is interested in connected devices and technology platforms which help consumers quit or reduce smoking as well as manage their respiratory health.  Areas of interest broadly include (but are not limited to):

• Improving the delivery and efficacy of behavioral support programs through greater personalization and customization via artificial intelligence, passive data collection, etc.
• Digital interventions that increase compliance with NRT.
• Digital interventions that improve the health and wellness of individuals trying to quit or reduce nicotine consumption.

Open Ended

If you could collaborate with GSK to improve any aspect of the lives of those struggling with a nicotine addiction, what would that be and how can GSK help?

Possible Approaches

Approaches

GSK notes that possible approaches might include, but are not limited to:

• Products, features, and/or services that provide at least an incremental improvement to current offerings.
• Current research that can inform or evolve GSK’s NRT portfolio or digital behavioral support platform.

Approaches not of Interest

Approaches that provide alternatives to smoking but do not promote a nicotine-free lifestyle are not of interest to GSK.

Items to be Submitted

Your response should address the following:

• The AREA OF INTEREST (as listed above) which your approach addresses
• A non-confidential description of your proposed technology and working principle
• Availability of technical data
• Technical maturity of the approach (concept, research, reduced to practice, prototype, ready to commercialize, ready to implement, commercialized)
• Pathway to commercial scale including timing, estimated budget, and capacity for manufacture
• Position on intellectual property including patent references
• Desired relationship with GSK
• Team description and related experience

Due Date: April 4, 2019

NineSights Community – Request for Proposal: ‪Polymers That Decompose at Low Temperatures‬

Opportunity

Licensing, product acquisition, proof of concept leading to scale-up to manufacturing, joint development, supplier agreement

Timeline

Phase 1 – Technology Assessment – 3 – 6 months

Phase 2 – Development plan / Scale-up – 12-24 months

Financials

All terms to be negotiated depending on technology status

SOLUTION PROVIDER HELP CONTACT

EMAIL: worsfold@ninesigma.com

RFP Title
Polymers That Decompose at Low Temperatures

RFP Description

NineSigma, representing a global high-performance materials manufacturer, invites proposals from organizations and researchers for polymers (fibres) that can decompose at low temperatures.

Background

Ninesigma’s client is a global supplier of high performance materials for a variety of high temperature applications.

The integration of polymer materials (fibres, etc.) into various product lines has a number of potential applications. The primary goal for the current search is to find a polymer matrix, blend or composition that decomposes at 100°C. Potential solutions which currently decompose at 250°C with a clear path to reducing (e.g. functionalising, processing, etc.) this decomposition temperature are also of high interest.

The decomposition temperature is linked to the fibre length and therefore consultants and/or academics who have extensive experience in this area are highly valued.

The client is open to all solutions from academia and from industry, as long as there is a clear understanding of the method and requirements.

Key Success Criteria

The ideal solution will be a polymer material / fibre which meets the following criteria:

• Decomposition temperature: 100°C
• Low melting point
• Fibre length: 3-6mm
• Fibre Diameter: micron range
• Final product polymer concentration <1%

Possible Approaches

Potential solutions could include, but are not limited to:

• Any polymer composition which has low decomposition temperature and low melting point
• Long length polymeric fibres
• Any green material systems

Items to be Submitted

Proposals should not include any confidential information and should contain the following:

• Executive summary
• Status of IP and Freedom to operate
• Brief overview of organization
• Experience of commercial exploitation of chemistry methodology development

For assistance, please contact the Programme Manager (worsfold@ninesigma.com).

NineSights Community – Request for Proposal: ‪Materials for Weather Protection of Buildings‬

Due Date: April 4, 2019

Opportunity

The RFP sponsor is open to a range of potential outcomes – licensing, technology acquisition, contract research, joint development, supplier agreement, etc

Timeline

Phase 1 – up to six (6) months from selection of submitted proposals during which the concept is validated/demonstrated and strategies for commercial development are developed

Phase 2 – 18-24 month period during which the technology is demonstrated in pilot line

Financials

Funding up to US$ 75,000 for development of a suitable solution.

Alternatively, the RFP sponsor will consider any reasonable business relationship with qualified partner(s) selected on the ability to address the issues described in this project.

RFP Title
Materials for Weather Protection of Buildings

RFP Description

NineSigma, representing a major building materials manufacturer, invites proposals for methods, materials, or novel approaches to re-inventing weather protection for residential buildings. The weather barrier may be directly exposed or behind a decorative façade, and should be able to withstand thermal, moisture, and UV environments for at least 10 years. Solutions that do not need a decorative façade, that provide lower installed/labor cost versus current solutions, or are cradle-to-cradle approaches are strongly preferred. Solutions that impact vapor barrier, roofing, or sheathing applications are also strongly preferred. The partner is open to a wide range of potential solutions (e.g., replacement with alternative substances, new material architectures, novel processing methods) that can achieve this objective.

Background

Residential homes in North America currently use 13.5 billion square feet of asphalt shingles, over 25 billion square feet of vapor barrier products, and billions of board feet of sheathing. The solutions for these markets are under intense pressure for a variety of reasons, including labor shortages, disposal/sustainability, and evolving building codes for fortified or storm-resistant building design.

The RFP sponsor is seeking novel approaches to weatherproofing for residential construction in North America. Potential solutions from adjacent industries are of significant interest to this client, including approaches that include new or novel materials, innovations in manufacturing processes, and engineering solutions.

Key Success Criteria

The technology must:

• Perform as well as, or better than, weatherproofing approaches currently used in commercial and residential buildings
• Maintain weatherproofing performance characteristics for a minimum of 10 years
• Be able to demonstrate protection from UV exposure, thermal conditions, moisture and vapor permeability without loss of mechanical integrity
• Demonstrate a clear path to high volume production
• Be able to reduce installed cost benefit for currently used approaches in conventional wood frame construction by at least 20%, ideally greater than 50%

Possible Approaches

Possible approaches might include, but are not limited to:

• Materials substitution, functional materials, engineered products, or material structures
• Weatherproofing agents or additives that impart weatherproofing properties in construction materials
• Modifications to current manufacturing processes
• Additive manufacturing (3-D Printing)
• Micro-scale structural reorganization
• Coatings, surface treatments, sealing agents, or other post-processing solutions

Approaches not of Interest

The following approaches are not of interest:

• Approaches that do not have a demonstrable path to high volume production, or that do not save labor
• Modifications of current weatherproofing approaches (e.g. asphalt, Tyvek, etc.) that do not significantly improve performance and/or meet the desired price point noted in this RFP
• Materials or solutions that cannot meet safety or toxicity standards for residential home construction in the U.S.
• Concepts, ideas, or any early-stage technology that has not yet been demonstrated at lab or pilot scale

Items to be Submitted

Your response should address the following:

• Non-confidential description of proposed technology and working principle
• Availability of technical data including weather resistance performance, MSDS, manufacturability, permeability, and durability
• Technical maturity of the approach (concept, reduced to practice, prototype, ready to commercialize, ready to implement, commercialized)
• Pathway to commercial scale including timing, estimated budget, and capacity for manufacture
• Estimated unit cost of proposed technology
• Position on intellectual property including patent references
• Desired relationship with sponsor
• Team description and related experience