Arcadia: Department of Defense Grant for Biofilm Research

The Defense Advanced Research Projects Agency (DARPA) is awarding grants to all responsible sources capable of providing research on biofilm, bacteria control and microbial community manipulation that will satisfy the United States Government. Experiments related to biofilm manipulation must be conducted in the laboratory as well as in the field to ensure real-world results that will help us understand and render biofilm beneficial to our government and society through for real-world applications.




No restrictions.


4 years


Proposal Abstract: October 25, 2021, 4:00 PM ET 
Full Proposal: December 15, 2021, 4:00 PM ET





For more information, visit the grant page.

NSF Transitions to Excellence in Molecular and Cellular Biosciences Research (Transitions)

Program Solicitation: NSF 20-505

Full Proposal Deadline: Proposals accepted anytime

Synopsis of Program

The Division of Molecular and Cellular Biosciences (MCB) has developed a new opportunity to enable researchers with a strong track record of prior accomplishment to pursue a new avenue of research or inquiry. This funding mechanism is designed to facilitate and promote a PI’s ability to effectively adopt empowering technologies that might not be readily accessible in the PI’s current research environment or collaboration network. Transformative research likely spans disciplines and minimizing the practical barriers to doing so will strengthen research programs poised to make significant contributions. The award is intended to allow mid-career or later-stage researchers (Associate or Full Professor, or equivalent) to expand or make a transition in their research programs via a sabbatical leave or similar mechanism of professional development and then develop that research program in their own lab. This award will also enable the PI to acquire new scientific or technical expertise, facilitate the investigator’s competitiveness, and potentially lead to transformational impacts in molecular and cellular bioscience. The award would fund up to six months of PI salary during the first sabbatical or professional development year, followed by support for continued research for two subsequent years upon the PI’s return to normal academic duties. Through this solicitation MCB and NSF hope to develop a novel mechanism that will encourage investigators to expand and/or transition to new research areas aligned with MCB priorities, to increase retention of investigators in science, and to ensure a diverse scientific workforce that remains engaged in active research.

Through the “Transitions to Excellence In Molecular and Cellular Biosciences Research” (Transitions Award) program, MCB is seeking proposals that (1) promote fundamental understanding of complex living systems at the molecular, subcellular, and cellular levels typical of its core research programs and (2) enable investigators with a strong prior track record of accomplishment to expand or change research direction, thus ensuring their continued competitiveness in science.

Core research programs in MCB place a high priority on projects that provide mechanistic insights that can be used predictively to establish and verify the rules governing life’s processes. MCB encourages proposals that address major biological questions at the intersections of biology with other disciplines, such as physics, chemistry, mathematics, computer sciences, and engineering.

The following cross-cutting areas of research, most notably where they elucidate the rules governing life’s processes, will be given high priority for funding in all clusters in MCB core programs.

  • Integrating Across Scales: Integrating knowledge from single molecules to molecular machines and from networks to subcellular and cellular complexity.
  • Transformative Methods and Resources: Developing technologies for molecular and cellular biology research (when motivated by compelling biological questions), including biophysical and computational methods for broad application and genetic resources for model systems.
  • Molecular and Cellular Evolution: Discovering mechanisms and theoretical underpinnings of evolutionary changes in molecules, genomes, and cells.
  • Synthesizing Life-Like Systems: Using synthetic molecular parts and processes to understand the transition from simple to complex systems and to build novel living systems.
  • Genomes to Phenomes: Integrating theoretical, computational, and high-throughput experimental approaches to determine and predict how the genome/epigenome gives rise to phenotype.

NSF Critical Aspects of Sustainability (CAS)

Economic development and human progress have led to a proliferation of manufactured chemicals and materials made from limited resources found in nature (i.e., minerals and metals, petroleum-based products and natural gas). Long-term sustainability requires consideration of the availability of specific natural resources, energy, and water usage. NSF continues to support efforts that seek to improve the efficiency with which natural resources are used to meet human needs for products and services. Sustainability research encompasses the design, manufacture and use of efficient, effective, safe and more environmentally-benign products and processes; stimulates innovation across all sectors to design and discover new chemicals and materials, production processes, and product stewardship practices; and, increases performance and value while meeting the goals of protecting and enhancing human health and the environment.

This program seeks to support basic research through core disciplinary programs aimed at improving the sustainability of resources for future generations while maintaining or improving current products in order to offer technologically-advanced, economically competitive, environmentally-benign and useful materials to a global society. In order to address these challenges, the program aims to identify opportunities for innovation in a wide range of contributing disciplines as well as integrative activities. This program encourages the development of new experimental and theoretical/modeling approaches that will aid in both reductionist and whole-systems approaches.

This program welcomes proposals in any area of research supported through the participating divisions that address the topics outlined below. The selected topics are of particular interest to core disciplinary programs in the participating divisions and do not include all funding opportunities and priorities in the area or sustainability at NSF. Proposals are submitted to the relevant core Programs indicated below in the participating Divisions, and all questions regarding proposals should be addressed by the cognizant Program Officers to which submission is contemplated. Proposals should be submitted with the “CAS:” prefix in the title.

The Division of Chemistry (CHE/MPS) welcomes proposals to its Disciplinary Research Programs, including Chemical Catalysis (CAT), Chemical Measurement and Imaging (CMI), Chemical Structure, Dynamics and Mechanisms-A (CSDM-A), Chemical Structure Dynamics and Mechanisms-B (CSDM-B), Chemical Synthesis (SYN), Chemical Theory, Models and Computational Methods (CTMC), Chemistry of Life Processes (CLP), Environmental Chemical Sciences (ECS), and Macromolecular, Supramolecular and Nanochemistry (MSN). All proposals must be on chemical aspects of sustainability.

The Division of Materials Research (DMR/MPS) welcomes proposals to its Topical Materials Research Programs, including Biomaterials (BMAT), Ceramics (CER), Condensed Matter and Materials Theory (CMMT), Condensed Matter Physics (CMP), Electronic and Photonic Materials (EPM), Metals and Metallic Nanostructures (MMN), Polymers (POL), and Solid State and Materials Chemistry (SSMC). All proposals must be on materials aspects of sustainability and focused on fundamental materials-research approaches.

The Chemical, Bioengineering, Environmental and Transport Systems Division (CBET/ENG) has several core programs that review proposals on research topics related to sustainability, including Molecular Separations (MolS), Biosensing, Environmental Sustainability (EnvS), Biological and Environmental Interactions of Nanoscale Materials (BioNano), Combustion and Fire Systems (CFS), and Particulate and Multiphase Processes (PMP).

For the Division of Civil, Mechanical and Manufacturing Innovation (CMMI/ENG), proposals addressing sustainable materials processing are welcome. Of interest are manufacturing processes with reduced use of toxic components, such as solvents, carbon emissions, and pollutants; processes under ambient conditions, as opposed to extreme temperatures, pressures or other harsh conditions; and increased conservation of natural resources, such as water, raw material, and energy. Proposals to CMMI must be submitted to the Advanced Manufacturing (AM) Program and align with the scope of the program.

The Division of Earth Sciences (EAR/GEO) welcomes fundamental and transformational geosciences projects addressing the distribution of Critical Minerals and Materials in the Earth. The following programs in the division support research on this topic: Petrology and Geochemistry (CH), Geobiology and Low-Temperature Geochemistry (GG), and Frontier Research in Earth Sciences (FRES).

For additional information, including due dates for specific NSF Divisions, please visit the CAS program page.