Biophotonics Imaging, Spectroscopy and Sensing (BISS) Lab

Publications

Book Chapters

  1. Bing Yu, Daron G. Ferris, and Vivek Krishna Nagarajan, “Mobile Fiber-Optic Sensor for Detection of Oral and Cervical Cancer in Developing World”, in Mobile Health Technologies – Methods and Protocols, Editors Avraham Rasooly and Keith E. Herold, Humana Press, 2015.
  2. Bing Yu and Nirmala Ramanujam, “Quantitative Diffuse Reflectance Imaging of Tumor Margins”, Chapter 17 in Biomedical Photonics Handbook, Editor-in-Chief Tuan Vo-Dinh, 2nd Edition, CRC Press, 2015.
  3. Bing Yu, “Servo System of a Magneto-Optical Disk Driver,” Chapter 2 of Part II in Magneto-Optical Recording Technology, UESTC Publisher, pp146-176, 1994 (in Chinese).

Journal Publications

  1. Bing Yu, Daron G. Ferris, Yang Liu and Vivek K. Nagarajan, “Emerging Optical Techniques for Detection of Oral, Cervical and Anal Cancer in Low-Resource Settings”, Austin Journal of Biomedical Engineering, Vol. 1, Issue 2:15, 2014. (Invited review article).
  2. Bing Yu, Amy Shah, Vivek K. Nagarajan, and Daron G. Ferris, “Diffuse reflectance spectroscopy of epithelial tissue with a smart fiber-optic probe,” Biomedical Optics Express Vol. 5, Iss. 3, pp. 675–689 (2014).
  3. Justin Y. Lo, J. Quincy Brown, Sulochana Dhar, Bing Yu, Gregory M. Palmer, Nan M. Jokerst, and Nirmala Ramanujam, “Wavelength optimization for quantitative spectroscopic imaging of breast tumor margins,” PLoS ONE 8(4): e61767. doi:10.1371/journal.pone.0061767 (2013).
  4. Sulochana Dhar, Justin Y. Lo, Greg Palmer, Martin A. Brooke, Brandon Nichols, Bing Yu, Nimmi Ramanujam, and Nan M. Jokerst, “A Diffuse Reflectance Spectral Imaging System for Tumor Margin Assessment Using Custom Annular Photodiode Arrays,” Biomedical Optics Express, Vol. 3, Issue 12, pp. 3211-3222 (2012).
  5. Bing Yu, Amy Shah, Bingqing Wang, Narasimhan Rajaram, Quanli Wang, Nirmala Ramanujam, Gregory M. Palmer, and Mark W. Dewhirst, “Measuring Tumor Cycling Hypoxia and Angiogenesis using a Side-firing Fiber Optic Probe,” Journal of Biophotonics, Dec 14, 2012, doi: 10.1002/jbio.201200187.
  6. Vivide T.C. Chang, Delson Merisier, Bing Yu, David K. Walmer,and Nirmala Ramanujam, “Towards a field-compatible optical Spectroscopic device for cervical cancer screening in resource-limited settings: effects of calibration and pressure,” Optics Express, Vol. 19, Iss. 19, pp. 17908–17924 (2011).
  7. B. Yu, H.L. Fu and N. Ramanujam, “Instrument-Independent Diffuse Reflectance Spectroscopy,” Journal of Biomedical Optics, vol. 16(1): p. 011010 (2011).
  8. H.L. Fu, B. Yu, J.Y. Lo, G.M. Palmer, T.F. Keuch, and N. Ramanujam, “A low-cost, portable, and quantitative spectral imaging system for application to biological tissues,” Optics Express, Vol. 18, Issue 12, pp. 12630-12645 (2010).
  9. J.Q. Brown, T.M. Bydlon, L.M. Richards, B. Yu, S.A. Kennedy, J. Geradts, L.G. Wilke, M. Junker, J. Gallagher, W. Barry, and N. Ramanujam, “Optical assessment of tumor resection margins in the breast,” Journal of Selected Topics in Quantum Electronics, vol. 16(3), pp. 530-544, 2010.
  10. T.M. Bydlon, S.A. Kennedy, L.M. Richards, J.Q. Brown, B. Yu, M.S. Junker, J. Gallagher, J. Geradts, L.G. Wilke, and N. Ramanujam, “Performance metrics of an optical spectral imaging system for intra-operative assessment of breast tumor margins”. Optics Express, Vol. 18, Issue 8, pp. 8058-8076 (2010).
  11. J.E. Bender, A.B. Shang, E.W. Moretti,B. Yu,L.M. Richards and N. Ramanujam, “Noninvasive monitoring of tissue hemoglobin using UV-VIS diffuse reflectance spectroscopy: a pilot study,” Optics Express, Vol. 17, Issue 26, pp. 23396-23409 (2009).
  12. C. Zhu, E.S. Burnside, G.A. Sisney, L.R. Salkowski, J.M. Harter, B. Yu and N. Ramanujam, “Fluorescence spectroscopy: an adjunct diagnostic tool to image-guided core needle biopsy of the breast,” IEEE Trans Biomed Eng. 2009 Oct;56(10):2518-28.
  13. J.Y. Lo, B. Yu, H.L. Fu, J.E. Bender, G.M. Palmer, T.F. Kuech and N. Ramanujam, “A strategy for quantitative spectral imaging of tissue absorption and scattering using light emitting diodes and photodiodes,” Optics Express. 17 (3):1372-1384, 2009.
  14. B. Yu, J.Y. Lo, T.F. Kuech, G.M. Palmer, J.E. Bender, N. Ramanujam, “A Cost-Effective Diffuse Reflectance Spectroscopy Device for Quantifying Tissue Absorption and Scattering In Vivo,” Journal of Biomedical Optics, Vol. 13, No. 6, 2008.
  15. B. Yu, H.L. Fu, T.M. Bydlon, J.E. Bender and N. Ramanujam, “Diffuse reflectance spectroscopy with a self-calibrating fiber optic probe,” Optics Letters, Vol. 33, Issue 16, pp. 1783-1785 (2008).
  16. B. Yu, E.S. Burnside, G.A. Sisney, J.M. Harter, C. Zhu, A.H. Dhalla and N Ramanujam, “Feasibility of near-infrared diffuse optical spectroscopy on patients undergoing image-guided core-needle biopsy,” Optics Express 15, pp. 7335-50 (2007).
  17. B. Yu, A. Wang, and G.R. Pickrell, “Analysis of Fiber Fabry-Perot Interferometric Sensors Using Low-Coherence Light Sources,” Journal of Lightwave Technology, vol. 24, no. 4. pp. 1758-67 (2006).
  18. B. Yu, A. Wang, G.R. Pickrell, and J. Xu, “Tunable Optical Filter Based White Light Interferometry for Sensing,” Optics Letters, vol. 30, no. 12, pp.1452-54 (2005).
  19. B. Yu, G.R. Pickrell, and A. Wang, “Thermally Tunable Extrinsic Fabry-Perot Filter,” IEEE Photonics Technology Letters, vol. 16, no. 10, pp. 2296-98 (2004).
  20. B. Yu and A. Wang, “Grating-assisted Demodulation of Interferometric Optical Sensors”, Applied Optics, vol. 42, no. 34, pp. 6824-29 (2003).
  21. B. Yu, D.-W. Kim, J. Deng, H. Xiao, and A. Wang, “Fiber Fabry-Perot sensors for detection of partial discharges in power transformers ”, Applied Optics, Vol.42, No.16, pp. 3241-50 (2003).
  22. B. Yu and B. Cai, “The Application Techniques of WDM in Optical SDH Communication Systems,” Optical Communication Technology, vol. 24, no. 86, pp.13-18, (2000) (in Chinese).

Conference Proceedings and Presentations

  1. Vivek Krishna Nagarajan, Bing Yu,”Real-time Monitoring of Thermal Damage in Ex-vivo Tissues Using Diffuse Reflectance Spectroscopy, ASLMS conference Lasers 2015, Kissimmee, April 2015.
  2. Xiangqian Hong and Bing Yu, “Assessing Tissue Hemoglobin and Oxygenation Using a Near-infrared Side-firing Fiber Optic Sensor”, 2015 Health and Human Performance Research Summit, Dayton, Ohio, April 28-30, 2015. (poster presentation)
  3. Vivek Krishna Nagarajan, Bing Yu, “Changes in tissue optical properties during thermal ablation of ex-vivo pork tissue”, 86th Annual National Technical Association Conference, Cleveland, 2014. [poster]
  4. Bing Yu, Amy Shah, and Vivek K. Nagarajan, “Diffuse reflectance spectroscopy of epithelial tissue with controlled probe-to-tissue pressure,” OSA Topic Meeting on Biomedical Optics (BIOMED), Miami Hilton Downtown, Miami, Florida, USA, 26 – 30 April 2014.
  5. Bing Yu, Amy Shah, Bingqing Wang, Narasimhan Rajaram, Quanli Wang, Nirmala Ramanujam, Gregory M. Palmer, and Mark W. Dewhirst, “Monitoring of cycling hypoxia and angiogenesis in FaDu head and neck tumors using a side-firing sensor,” Proc. SPIE 8578, Optical Tomography and Spectroscopy of Tissue X, 85781E (March 25, 2013); doi:10.1117/12.2002837 (Invited paper).
  6. Justin Y. Lo, Sulochana Dhar, Bing Yu, Martin A. Brooke, Thomas F. Kuech, Nan M. Jokerst and Nimmi Ramanujam, “Diffuse reflectance spectral imaging for breast tumor margin assessment”, Proc. SPIE 8214, 821407 (2012).
  7. B. Yu, J.Q. Brown, T.M. Bydlon, M. Junker, J. Geradts, S. Pruitt and N. Ramanujam, “Quantitative Diffuse Reflectance Imaging of Breast Tumor Margins,” 2011 The 3rd National Optics Research Forum for Yong Scientists, November 11-15, Chengdu, China. (Invited Talk)
  8. B. Yu, V. Chang, A. Shah, D. Merisier, D. Walmer and N. Ramanujam, “A smart fiber optic sensor for cervical cancer detection in developing world,” the 10th International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2011) on November 2-5, 2011 in Wuhan, P. R. China.
  9. S. Dhar, J.Y. Lo, B. Yu, T. Tyler, M.A. Brooke, T.F. Kuech, N. Ramanujam, N.M. Jokerst, “A custom wide-field spectral imager for breast cancer margin assessment,” IEEE Photonic Society 24th Annual Meeting, PHO 2011 2011:798-799.
  10. S. Dhar, J.Y. Lo, B. Yu, M.A. Brooke, N. Ramanujam and N.M. Jokerst, “Custom Annular Photodetector Arrays for Breast Cancer Margin Assessment Using Diffuse Reflectance Spectroscopy,” 2011 IEEE Biomedical Circuits & Systems Conference, San Diego, California, November 10-12, 2011.
  11. B. Yu, V. Chang, A. Shah, D. Merisier, D. Walmer and N. Ramanujam, “A smart fiber optic sensor for detection of oral and cervical cancer in developing world,” NIH/NCI Cancer Detection and Diagnostics Technologies for Global Health Conference, August 22-23, 2011 at the NIH Campus. (poster and invited technology demo).
  12. B. Yu, J.Q. Brown, J.Y. Lo, T.M. Bydlon, H.L. Fu, S.A. Kennedy, M. Junker, T.F. Kuech, J. Geradts, L.G. Wilke and N. Ramanujam, “Quantitative Spectral Imaging for Intraoperative Breast Tumor Margin Assessment,” European Conference on Biomedical Optics 2011, 22 – 26 May 2011, Munich, Germany. (Invited talk)
  13. B. Yu, G.M. Palmer, B. Wang, A. Shah, K. Vishwanath and N. Ramanujam, “Monitoring of Head and Neck Tumor Physiology in Response to Hyperoxia using a Side-firing Fiber Optic Probe,” European Conference on Biomedical Optics 2011, 22 – 26 May 2011, Munich, Germany. (poster presentation)
  14. V. Chang, D. Merisier, B. Yu, D.K. Walmer and N. Ramanujam, “Calibration schemes of a field-compatible optical spectroscopic system to quantify neovascular changes in the dysplastic cervix,” accepted for oral presentation by Photonics West 2011 (BiOS), 22-27 Jan. 2011, San Francisco, CA.
  15. J.Y. Lo, B. Yu, H. Fu, T.F. Kuech and N. Ramanujam, “A compact, cost-effective diffuse reflectance spectroscopic imaging system for quantitative tissue absorption and scattering,” Proceedings of SPIE Vol. 7890, 78900B (2011).
  16. B. Yu, H. Fu and N. Ramanujam, “UV-visible Diffuse Reflectance Spectroscopy with a Self-calibrating Fiber Optic Probe,” ECI Conference on Advances in Optics for Biotechnology, Medicine and Surgery XI Clinical Challenges and Research Solutions, June 28 – July 2, 2009, Burlington, Vermont, USA. (Best Poster Award)
  17. J.E. Bender, B. Yu, A.B. Shang, E.W. Moretti,L.M. Richards and N. Ramanujam “Noninvasive Monitoring of Blood Loss Using Diffuse Reflectance Spectroscopy:  A Preliminary Patient Study,” ECI Conference on Advances in Optics for Biotechnology, Medicine and Surgery XI Clinical Challenges and Research Solutions, June 28 – July 2, 2009, Burlington, Vermont, USA.
  18. H.L. Fu, B. Yu, J.Y. Lo, T.F. Kuech, and N. Ramanujam, “A Low Cost System for Quantitative Spectral Imaging of Tissue Absorption and Scattering,” ECI Conference on Advances in Optics for Biotechnology, Medicine and Surgery XI Clinical Challenges and Research Solutions, June 28 – July 2, 2009, Burlington, Vermont, USA.
  19. B. Yu, H.L. Fu, T.M. Bydlon, J.E. Bender, and N. Ramanujam, “A Self-Calibrating Fiber Optic Probe for Tissue Optical Spectroscopy,” CLEO 2008, May 6-8, 2008, San Jose, CA.
  20. J.Y. Lo, B. Yu, G.M. Palmer, T.F. Kuech and N. Ramanujam, “A Miniature Optical Device for Noninvasive, Fast Characterization of Tumor Pathology,” 2008 OSA Topic Meeting in Biomedical Optics, March 16-19, 2008, St. Petersburg, Florida.
  21. B. Yu, C. Lubawy, C. Zhu, E.S. Burnside, G.A. Sisney and N. Ramanujam, “Fiber Optic Probe Based-on Near Infrared Spectroscopy for Improving the Accuracy of Breast Core Needle Biopsy,” invited poster presentation at the Annual NIH/NIBIB Grantee Meeting, August 8-9, 2005, Washington, DC.
  22. X. Wang, J. Xu, Y. Zhu,B. Yu, M. Han, K.L. Cooper, G.R. Pickrell, and A. Wang, “An optical fiber tip pressure sensor for medical applications,” Quantum Electronics and Laser Science Conference 2005, vol. 2,  pp. 916- 918, May 2005.
  23. X. Wang, J. Xu, B. Yu, K.L. Cooper, A. Wang, “Implementation of nondestructive Young’s modulus measurement by miniature optical sensors,” Proceedings of SPIE Vol. 5998, 23-26 Oct. 2005.
  24. J. Xu, G.R. Pickrell, X. Wang, B. Yu, K.L. Cooper, A. Wang, “Vacuum-sealed high temperature high bandwidth fiber optic pressure and acoustic sensors,” Proceedings of SPIE Vol. 5998, 23-26 Oct. 2005.
  25. X. Wang, J. Xu, Y. Zhu, B. Yu, M. Han, K.L. Cooper, G.R. Pickrell, A. Wang, A. Ringshia, W. Ng, “Verifying an all fused silica miniature optical fiber tip pressure sensor performance with turbine engine field test,” Proceedings of SPIE Vol. 5998, 23-26 Oct. 2005.
  26. B. Yu and A. Wang, “Tunable Extrinsic Fabry-Perot Filter for Sensing Applications”, 2004 Optics in the Southeast, SE04-A2, November 4 – 5, 2004, Charlotte, North Carolina.
  27. B. Yu, G.R. Pickrell, D.-W. Kim, and A. Wang, “Thermally tunable extrinsic Fabry-Perot filter for white-light interferometry,” in Frontiers in Optics, OSA Technical Digest Series (Optical Society of America, 2004), paper FWH23.
  28. B. Yu, A. Wang, and G.R. Pickrell, “Analysis of White-light Fiber Fabry-Perot Interferometric Sensors”, Proc. of SPIE, Fiber Optic Sensor Technology and Applications III, Edited by Michael A. Marcus, Brian Culshaw, John P. Dakin, Vol. 5589, 2004.
  29. J. Xu, G.R. Pickrell, B. Yu, M. Han, Y. Zhu, X. Wang, K.L. Cooper, and A. Wang, “Epoxy-free high temperature fiber optic pressure sensors for gas turbine engine applications,” Proc. of SPIE, Sensors for Harsh Environments, Edited by Anbo Wang, Vol. 5590, 2004.
  30. Y. Zhu, G.R. Pickrell, X. Wang, J. Xu, B. Yu, M. Han, K.L. Cooper, A. Wang, A. Ringshia, and W. Ng, “Miniature fiber-optic pressure sensor for turbine engine,” Proc. of SPIE, Sensors for Harsh Environments, Edited by Anbo Wang, Vol. 5590, 2004.
  31. X. Chen, B. Yu, Y. Zhu and A. Wang, “Deep wet etching of fused silica material for fiber optic sensor fabrication,” Proc. of the SPIE, vol. 5342, pp. 128-136, 2004.
  32. B. Yu, G.R.. Pickrell and A. Wang, “Grating-assisted Operation-Point Tuning for Fiber-Optic Fabry-Perot Interferometric Sensors,” Proc. of the SPIE, vol. 5272, pp. 41-48, 2004.
  33. D.-W. Kim, B. Yu, Y. Song, A. Wang, Y. Liu, A. Shahsiah, R. Degeneff, B. Ward, “Discharge and Thermal Gassing Monitoring using Fiber Acoustic Sensors,” EPRI Substation Equipment Diagnostics Conference XII, February 15-18, 2004, New Orleans, Louisiana.
  34. B. Yu, D.-W. Kim, J. Deng, B. Ward, W. Cockey, Y. Liu and A. Wang, “Fiber Optic Sensors for Partial Discharge Monitoring in Power Transformers”, 2003 EPRI Substation Equipment Diagnostics Conference, Feb. 23-26, 2003, New Orleans, Louisiana.
  35. Steven Tsai, Bing Yu, Ling Chen, Anbo Wang, Yilu Liu, Barry Ward, “Analysis of on-site transformer partial discharge measurement from fiber optic acoustic sensors”, 2003 EPRI Substation Equipment Diagnostics Conference, Feb. 23-26, 2003, New Orleans, Louisiana.
  36. Ling Chen, Steven Tsai, Yilu Liu*, Bing Yu, Anbo Wang, Barry Ward, “Finite Element Simulation and Theoretical Analysis of the Partial Discharge Acoustic Wave Propagation inside Power Transformers”, 2003 EPRI Substation Equipment Diagnostics Conference, Feb. 23-26, 2003, New Orleans, Louisiana.